The greatest factor in whether this is possible is whether development is continuing on the game or not. 

If the game continues to receive new content updates over time even four years after release (e.g. Street Fighter V released in 2016 and has recently received its final update), then a sufficiently sized group of entrenched community players may be persuasive enough to get the developer to devote engineering resources to remove the DRM. In order to be persuasive enough, you need to rally the game’s community to your cause - sufficient to the point that the game’s community managers recognize it and pass that feedback to the development team as a thing the community cares about. The game’s producers will figure out whether doing so is worth it and (possibly) move forward with the DRM removal if the cost isn’t too great.

If the game has not received content updates in a long time, then the chances of success drop to near zero. The reason for this is because it is highly likely that the development team members have already been reassigned to new projects and the game has been left to its own devices. In such a situation, even if there are developers at the company with the expertise to remove Denuvo and deploy that update, their schedules are likely filled with their new assignments. I’ve mentioned before that [it is very rare for developers to work on more than one project at once] - we usually devote all of our attention to a single project in order to minimize the costs of context switching. If there’s no one on the team doing active development, there’s no chance anyone is available to remove the DRM.

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